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Daily Archives: March 13, 2018


Jim Plante: An Innovative Mind in the Field of Biotech

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The field of biotechnology has been making dramatic leaps forward in recent years, thanks in large part to the contributions of investors and technology leaders such as Jim Plante. Mr. Plante began his professional career at Southern Illinois University, earning a degree in Electrical Engineering before going on to play an integral role in launching new and innovative biotech products.

The Early Years

Mr. Plante’s first step into the field of advanced biotechnology was to aide in the acquisition of the well-known company Beltronics. As the company’s interim president, Mr. Plante was able to facilitate the launch of innovative new product lines that allowed the company to turn around and make it back into the green within just one year. He went on to co-found another company, E-Band Communications, which went on to make historic changes in mobile wireless infrastructure systems and to found the company responsible for the innovative SAAS vehicle safety program.

Mr. Plante’s Life Work

After dipping his toes in the water working with these successful industry giants, Mr. Plante began to work in earnest toward accomplishing his life’s work. As a founder and CEO of Pathway Genomics and chairman of its Board of Directors, Mr. Plante was able to facilitate advances in genetic testing that have had an incredible impact on this important industry.

Mr. Plante became inspired to work in the field of medical biotechnology nearly three decades ago upon discovering that his father was suffering from polycystic kidney disease, a serious hereditary genetic condition. Although his father did not receive this diagnosis until it was too late for a successful kidney transplant, Mr. Plante himself received an early diagnosis thanks in part to genetic testing. This gave him the drive to help ensure that others would have access to affordable testing, offering countless others to take advantage of this advanced technology to provide for their own health and that of their children.

Pathway Genomics now offers the widest range of genetic testing in its industry, allowing the examination of patient genomes to be used to detect inherited genetic risks and offer insight into potential patient responses to commonly prescribed medications. Mr. Plante continues to perform this valuable work within the healthcare industry through a biotech investment firm known as Thynk Capital. Learn more about his innovative work online today.


Al Masah Capital Management Highlights Three Middle East Industries of Particular Promise

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Whereas economic growth across much of the world is slowing down, one region is still heating up. With positive projections for the Middle East and North Africa prevailing, investors from many other places are looking to get involved.

One of the easiest ways to do so, in many cases, is to work with an informed insider like Al Masah Capital Management. By focusing on alternative investments in industries that are likely to grow most quickly, this company and others like it can provide truly valuable assistance.

Three Industries Top the Charts When It Comes to Alternative Investments in the Middle East

A look at a few recent Al Masah projects will reveal that there are at least three industries investors will do well to investigate. Some of these detailed on the company’s website include:

  • Food and beverage. Relative to its impressive level of overall economic development, the Middle East has lagged somewhat behind other parts of the world with regard to commercial food and beverage services provided at scale. That is starting to change quickly, however, with a number of ambitious companies now making their individual marks all across the region. What was formerly the domain of mostly small, individually owned operations is beginning to look a lot more like the norms elsewhere in the world, and investors can easily benefit.
  • Education. Demand for advanced education in the Middle East and throughout North Africa has been rising steadily for years. Instead of being forced to head overseas for their studies, residents of more countries across the region are now intent on remaining closer to home. As a result, education providers have seen steadily growing demand for their services for many years, a trend that has already benefited many investors.
  • Healthcare. As one of the world’s wealthiest regions, the Middle East and North Africa is no longer content with healthcare services that do not represent the state of the art. An undeniable wave of modernization and expansion has been buoying the fortunes of healthcare companies throughout this part of the world.

Investing and Succeeding in the Middle East

For investors who rely upon partners that are capable of spotting opportunities like these, succeeding in this region becomes far easier. That is good news for the many who have found that a slowing pace of growth across much of the rest of the world makes looking elsewhere appealing.


Klotho Therapeutics Founder Jim Plante Has Goals for Biotech Treatment of Kidney Disease

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Biotechnology companies like Klotho Therapeutics are working with enzymes and proteins that occur naturally in the body and have positive effects on longevity and disease prevention. Founded by technology entrepreneur Jim Plante, who also founded Pathway Genomics, Klotho Therapeutics is currently concentrating on slowing the progression of kidney disease. Millions of U.S. residents suffer from kidney disease, with about 600,000 of them being treated with dialysis.

About the Klotho Gene and Its Protein

The klotho gene was first discovered in 1997. Scientists first conducted research on this gene and its associated protein in mice. They discovered that low amounts of the klotho protein or a mutation of the gene led to faster development of issues connected with aging. In contrast, overabundance of this protein was connected with greater longevity. The protein naturally circulates in the body for an entire lifetime, but levels decrease as people get older.

Relevant Studies

Research has since indicated that people suffering from chronic kidney disease always have a problem with phosphate retention, which in turn is connected with a deficiency of the klotho protein. A study published in 2011 says this finding suggests chronic kidney disease may be considered a condition of accelerated aging.

Further studies note that low levels of this protein might be considered an early indicator of kidney disease in addition to being a contributing factor in the illness. Researchers believe low levels may also be implicated in other health problems that include cancer, cardiovascular disease and dementia. The risk of all these illnesses increases with age.

A Word of Caution

Some websites claim that people can boost their levels of the protein through natural means such as exercise and changes in diet. However, the higher amounts in the circulation are unlikely to be remarkable enough or effective enough for any noticeable and practical improvements in the body. Biotechnology is the best option for increasing circulating klotho protein.

Clinical Trials

The team at Klotho Therapeutics intends to begin clinical trials with humans in the near future, possibly within two years. The trials will offer the results of the company’s biotechnology developments to people with chronic kidney disease.


Selling a Business? Be Smart With and Establish an Improvement Budget

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When a business owner is looking to sell their business, whatever the reasons are, hiring a broker is a good idea. Often times, one of the first things a broker will do is assess the current value of the business. In some cases, the assessed value is good for the owner, and the only thing left to do is to list the business for sale. However, if the value is under what the owner either wants or needs in the sale of the business, there are things an owner can do to improve the value of the business.

Improve the Value of a Business

While some things may not take a great deal of money, there are times where paying off debt and paying for physical improvements to the facility will need to be done in order to improve the businesses resale value. The tricky part is doing so in a manner that is financially responsible.

Value for Money Spent

People often times will put a bit of money into fixing up their home in order to fetch a higher listing price, and the same premise is used when selling a business. Sometimes the money needed to improve a business facility is substantial. However, it is important to understand the fiscal responsibility that is needed to make the money spent to improve the facility a wise investment.

Be Smart

In order to improve the value of a business, the owner is free to spend as much money as they want. The problem is, some people spend money on areas that cannot be recouped in the selling price. The key is to get the most value out of the money spent on facility improvements.

Spending $50,000 to improve a dentist office, for example, only to see the value increase by $30,000 is a bad investment. However, if $20,000 in improvements can net an increased value of $40,000 to $50,000 in the final sale price, then the money spent becomes a tremendous investment.

Your business facility may indeed require improvements to increase the asking price, but getting the most value out of your renovation budget is essential. Do this right, and you could very easily get the asking price you either want or need when it comes time to sell your business.


Al Masah Capital Management Helps Clients Make the Most of Alternative Investments in MENA

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The Middle East and North Africa, or MENA, is a region of immense resources, impressive economic development, and vast potential. As a result, it has increasingly become a point of particular focus for investors from elsewhere in the world.

For many investors, this ends up meaning little more than dabbling in the public equity markets. Others, however, are interested in alternative styles of investments that can potentially produce even more significant returns. Companies like Al Masah Capital Management specialize in locating such opportunities and helping investors make the most of them.

Looking Beyond Stocks and Bonds

Many investors are content to stick to trading equities and bonds wherever in the world they might focus their activities the most. While that can be a rewarding approach to the discipline, it can also be a limiting one.

So-called “alternative” investments often end up producing more impressive returns than could be obtained on established public markets. This is even more frequently the case in places like MENA, where there are far more such opportunities, relative to the publicly listed and traded options, than is usual elsewhere.

On the other hand, it can be difficult for individual investors to even identify alternative investments that could end up being worthwhile. Investment companies that take on this challenging work themselves can make things much easier.

Many Alternative Means of Investing in MENA

Just as with other parts of the world, there are many common alternative investment approaches in MENA. Two of the most important include:

  • Private equity. Taking a publicly traded company private or acquiring an ownership stake in one that has always been privately held can open up especially attractive opportunities. The freedom and latitude that comes with private ownership often enable options that would not otherwise exist.
  • Real estate. Many of the most lucrative MENA investment projects in recent times have centered around real estate. Investment specialists who create real estate focused funds for investors to participate in can help their clients realize especially impressive results.

Combined with the inherent potential that so many see in MENA, investment approaches like these can make for especially attractive options. Working with an investment company that focuses on such projects will often prove to be particularly rewarding.